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Base changes in tumour DNA have the power to reveal the causes and evolution of cancer
Next-generation sequencing (NGS) technology has demonstrated that the cancer genomes are peppered with mutations. Although most somatic tumour mutations are unlikely to have any role in the cancer process per se, the spectra of DNA sequence changes in tumour mutation catalogues have the potential to...
Autores principales: | Hollstein, M, Alexandrov, L B, Wild, C P, Ardin, M, Zavadil, J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241425/ https://www.ncbi.nlm.nih.gov/pubmed/27270430 http://dx.doi.org/10.1038/onc.2016.192 |
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