Mice with Catalytically Inactive Cathepsin A Display Neurobehavioral Alterations

The lysosomal carboxypeptidase A, Cathepsin A (CathA), is a serine protease with two distinct functions. CathA protects β-galactosidase and sialidase Neu1 against proteolytic degradation by forming a multienzyme complex and activates sialidase Neu1. CathA deficiency causes the lysosomal storage dise...

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Detalles Bibliográficos
Autores principales: Calhan, O. Y., Seyrantepe, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241486/
https://www.ncbi.nlm.nih.gov/pubmed/28133419
http://dx.doi.org/10.1155/2017/4261873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241486/
https://www.ncbi.nlm.nih.gov/pubmed/28133419
http://dx.doi.org/10.1155/2017/4261873

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