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Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle
AMP-activated protein kinase (AMPK) plays diverse roles and coordinates complex metabolic pathways for maintenance of energy homeostasis. This could be explained by the fact that AMPK exists as multiple heterotrimer complexes comprising a catalytic α-subunit (α1 and α2) and regulatory β (β1 and β2)-...
Autores principales: | Bultot, Laurent, Jensen, Thomas E., Lai, Yu-Chiang, Madsen, Agnete L. B., Collodet, Caterina, Kviklyte, Samanta, Deak, Maria, Yavari, Arash, Foretz, Marc, Ghaffari, Sahar, Bellahcene, Mohamed, Ashrafian, Houman, Rider, Mark H., Richter, Erik A., Sakamoto, Kei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241553/ https://www.ncbi.nlm.nih.gov/pubmed/27577855 http://dx.doi.org/10.1152/ajpendo.00237.2016 |
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