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High Efficiency Hydrodynamic DNA Fragmentation in a Bubbling System

DNA fragmentation down to a precise fragment size is important for biomedical applications, disease determination, gene therapy and shotgun sequencing. In this work, a cheap, easy to operate and high efficiency DNA fragmentation method is demonstrated based on hydrodynamic shearing in a bubbling sys...

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Detalles Bibliográficos
Autores principales: Li, Lanhui, Jin, Mingliang, Sun, Chenglong, Wang, Xiaoxue, Xie, Shuting, Zhou, Guofu, van den Berg, Albert, Eijkel, Jan C. T., Shui, Lingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241652/
https://www.ncbi.nlm.nih.gov/pubmed/28098208
http://dx.doi.org/10.1038/srep40745