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High Efficiency Hydrodynamic DNA Fragmentation in a Bubbling System
DNA fragmentation down to a precise fragment size is important for biomedical applications, disease determination, gene therapy and shotgun sequencing. In this work, a cheap, easy to operate and high efficiency DNA fragmentation method is demonstrated based on hydrodynamic shearing in a bubbling sys...
Autores principales: | Li, Lanhui, Jin, Mingliang, Sun, Chenglong, Wang, Xiaoxue, Xie, Shuting, Zhou, Guofu, van den Berg, Albert, Eijkel, Jan C. T., Shui, Lingling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241652/ https://www.ncbi.nlm.nih.gov/pubmed/28098208 http://dx.doi.org/10.1038/srep40745 |
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