Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson’s disease

Aging, genetics and environmental toxicity are important etiological factors in Parkinson’s disease (PD). However, its pathogenesis remains unclear. A major obstacle is the lack of an appropriate experimental model which incorporates genetic susceptibility, aging and prolonged environmental toxicity...

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Detalles Bibliográficos
Autores principales: Liu, Hui-Fang, Ho, Philip Wing-Lok, Leung, Gideon Chi-Ting, Lam, Colin Siu-Chi, Pang, Shirley Yin-Yu, Li, Lingfei, Kung, Michelle Hiu-Wai, Ramsden, David Boyer, Ho, Shu-Leong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241661/
https://www.ncbi.nlm.nih.gov/pubmed/28098219
http://dx.doi.org/10.1038/srep40887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241661/
https://www.ncbi.nlm.nih.gov/pubmed/28098219
http://dx.doi.org/10.1038/srep40887

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