Strain-specific Fibril Propagation by an Aβ Dodecamer

Low molecular weight oligomers of amyloid-β (Aβ) have emerged as the primary toxic agents in the etiology of Alzheimer disease (AD). Polymorphism observed within the aggregation end products of fibrils are known to arise due to microstructural differences among the oligomers. Diversity in aggregate...

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Detalles Bibliográficos
Autores principales: Dean, Dexter N., Das, Pradipta K., Rana, Pratip, Burg, Franklin, Levites, Yona, Morgan, Sarah E., Ghosh, Preetam, Rangachari, Vijayaraghavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241678/
https://www.ncbi.nlm.nih.gov/pubmed/28098204
http://dx.doi.org/10.1038/srep40787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241678/
https://www.ncbi.nlm.nih.gov/pubmed/28098204
http://dx.doi.org/10.1038/srep40787

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