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Strain-specific Fibril Propagation by an Aβ Dodecamer
Low molecular weight oligomers of amyloid-β (Aβ) have emerged as the primary toxic agents in the etiology of Alzheimer disease (AD). Polymorphism observed within the aggregation end products of fibrils are known to arise due to microstructural differences among the oligomers. Diversity in aggregate...
Autores principales: | Dean, Dexter N., Das, Pradipta K., Rana, Pratip, Burg, Franklin, Levites, Yona, Morgan, Sarah E., Ghosh, Preetam, Rangachari, Vijayaraghavan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241678/ https://www.ncbi.nlm.nih.gov/pubmed/28098204 http://dx.doi.org/10.1038/srep40787 |
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