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Hepatitis B virus X protein is capable of down-regulating protein level of host antiviral protein APOBEC3G

The apolipoprotein B mRNA editing catalytic polypeptide-like (APOBEC) family proteins bind RNA and single-stranded DNA, and create C-to-U base modifications through cytidine deaminase activity. APOBEC3G restricts human immunodeficiency virus 1 (HIV-1) infection by creating hypermutations in proviral...

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Detalles Bibliográficos
Autores principales: Chen, Ruidong, Zhao, Xue, Wang, Yongxiang, Xie, Youhua, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241686/
https://www.ncbi.nlm.nih.gov/pubmed/28098260
http://dx.doi.org/10.1038/srep40783