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The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia
Bacterial pneumonia is a significant healthcare burden worldwide. Failure to resolve inflammation after infection precipitates lung injury and an increase in morbidity and mortality. Gram-negative bacteria are common in pneumonia and increased levels of the mito-damage-associated molecular pattern (...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241690/ https://www.ncbi.nlm.nih.gov/pubmed/28074841 http://dx.doi.org/10.1038/ncomms13944 |