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The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia

Bacterial pneumonia is a significant healthcare burden worldwide. Failure to resolve inflammation after infection precipitates lung injury and an increase in morbidity and mortality. Gram-negative bacteria are common in pneumonia and increased levels of the mito-damage-associated molecular pattern (...

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Detalles Bibliográficos
Autores principales: Chakraborty, Krishnendu, Raundhal, Mahesh, Chen, Bill B., Morse, Christina, Tyurina, Yulia Y., Khare, Anupriya, Oriss, Timothy B., Huff, Rachael, Lee, Janet S., St. Croix, Claudette M., Watkins, Simon, Mallampalli, Rama K., Kagan, Valerian E., Ray, Anuradha, Ray, Prabir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241690/
https://www.ncbi.nlm.nih.gov/pubmed/28074841
http://dx.doi.org/10.1038/ncomms13944