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Cullin 7 mediates proteasomal and lysosomal degradations of rat Eag1 potassium channels

Mammalian Eag1 (Kv10.1) potassium (K(+)) channels are widely expressed in the brain. Several mutations in the gene encoding human Eag1 K(+) channel have been associated with congenital neurodevelopmental anomalies. Currently very little is known about the molecules mediating protein synthesis and de...

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Detalles Bibliográficos
Autores principales: Hsu, Po-Hao, Ma, Yu-Ting, Fang, Ya-Ching, Huang, Jing-Jia, Gan, Yu-Ling, Chang, Pei-Tzu, Jow, Guey-Mei, Tang, Chih-Yung, Jeng, Chung-Jiuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241692/
https://www.ncbi.nlm.nih.gov/pubmed/28098200
http://dx.doi.org/10.1038/srep40825