Enhancement of blood-tumor barrier permeability by Sar-[D-Phe8]des-Arg9BK, a metabolically resistant bradykinin B1 agonist, in a rat C6 glioma model

BACKGROUND: While it is well known that bradykinin B2 agonists increase plasma protein extravasation (PPE) in brain tumors, the bradykinin B1 agonists tested thus far are unable to produce this effect. Here we examine the effect of the selective B1 agonist bradykinin (BK) Sar-[D-Phe8]des-Arg9BK (SAR...

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Detalles Bibliográficos
Autores principales: Cardoso, Ronie Cleverson, Lobão-Soares, Bruno, Bianchin, Marino Muxfeldt, Carlotti, Carlos Gilberto, Walz, Roger, Alvarez-Silva, Márcio, Trentin, Andréa Gonçalves, Nicolau, Mauro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524173/
https://www.ncbi.nlm.nih.gov/pubmed/15458573
http://dx.doi.org/10.1186/1471-2202-5-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524173/
https://www.ncbi.nlm.nih.gov/pubmed/15458573
http://dx.doi.org/10.1186/1471-2202-5-38

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