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Enhancement of blood-tumor barrier permeability by Sar-[D-Phe8]des-Arg9BK, a metabolically resistant bradykinin B1 agonist, in a rat C6 glioma model
BACKGROUND: While it is well known that bradykinin B2 agonists increase plasma protein extravasation (PPE) in brain tumors, the bradykinin B1 agonists tested thus far are unable to produce this effect. Here we examine the effect of the selective B1 agonist bradykinin (BK) Sar-[D-Phe8]des-Arg9BK (SAR...
Autores principales: | Cardoso, Ronie Cleverson, Lobão-Soares, Bruno, Bianchin, Marino Muxfeldt, Carlotti, Carlos Gilberto, Walz, Roger, Alvarez-Silva, Márcio, Trentin, Andréa Gonçalves, Nicolau, Mauro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524173/ https://www.ncbi.nlm.nih.gov/pubmed/15458573 http://dx.doi.org/10.1186/1471-2202-5-38 |
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