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Centrality in the host–pathogen interactome is associated with pathogen fitness during infection

To perform their functions proteins must interact with each other, but how these interactions influence bacterial infection remains elusive. Here we demonstrate that connectivity in the host–pathogen interactome is directly related to pathogen fitness during infection. Using Y. pestis as a model org...

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Detalles Bibliográficos
Autores principales: Crua Asensio, Núria, Muñoz Giner, Elisabet, de Groot, Natalia Sánchez, Torrent Burgas, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241799/
https://www.ncbi.nlm.nih.gov/pubmed/28090086
http://dx.doi.org/10.1038/ncomms14092