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Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA
The hallmark of Salmonella Typhimurium infection is an acute intestinal inflammatory response, which is mediated through the action of secreted bacterial effector proteins. The pro-inflammatory Salmonella effector SopA is a HECT-like E3 ligase, which was previously proposed to activate host RING lig...
Autores principales: | Fiskin, Evgenij, Bhogaraju, Sagar, Herhaus, Lina, Kalayil, Sissy, Hahn, Marcel, Dikic, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241803/ https://www.ncbi.nlm.nih.gov/pubmed/28084320 http://dx.doi.org/10.1038/ncomms14004 |
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