Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease

Tissue macrophage numbers vary during health versus disease. Abundant inflammatory macrophages destruct tissues, leading to atherosclerosis, myocardial infarction and heart failure. Emerging therapeutic options create interest in monitoring macrophages in patients. Here we describe positron emission...

Descripción completa

Detalles Bibliográficos
Autores principales: Keliher, Edmund J., Ye, Yu-Xiang, Wojtkiewicz, Gregory R., Aguirre, Aaron D., Tricot, Benoit, Senders, Max L., Groenen, Hannah, Fay, Francois, Perez-Medina, Carlos, Calcagno, Claudia, Carlucci, Giuseppe, Reiner, Thomas, Sun, Yuan, Courties, Gabriel, Iwamoto, Yoshiko, Kim, Hye-Yeong, Wang, Cuihua, Chen, John W., Swirski, Filip K., Wey, Hsiao-Ying, Hooker, Jacob, Fayad, Zahi A., Mulder, Willem J. M., Weissleder, Ralph, Nahrendorf, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241815/
https://www.ncbi.nlm.nih.gov/pubmed/28091604
http://dx.doi.org/10.1038/ncomms14064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241815/
https://www.ncbi.nlm.nih.gov/pubmed/28091604
http://dx.doi.org/10.1038/ncomms14064

Ejemplares similares