Experimental Design and Data Analysis Issues Contribute to Inconsistent Results of C-Bouton Changes in Amyotrophic Lateral Sclerosis

The possible presence of pathological changes in cholinergic synaptic inputs [cholinergic boutons (C-boutons)] is a contentious topic within the ALS field. Conflicting data reported on this issue makes it difficult to assess the roles of these synaptic inputs in ALS. Our objective was to determine w...

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Detalles Bibliográficos
Autores principales: Dukkipati, S. Shekar, Chihi, Aouatef, Wang, Yiwen, Elbasiouny, Sherif M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
Failure to Replicate
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241941/
https://www.ncbi.nlm.nih.gov/pubmed/28101533
http://dx.doi.org/10.1523/ENEURO.0281-16.2016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241941/
https://www.ncbi.nlm.nih.gov/pubmed/28101533
http://dx.doi.org/10.1523/ENEURO.0281-16.2016

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