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Human β-defensin-2 production from S. cerevisiae using the repressible MET17 promoter

BACKGROUND: Baker’s yeast Saccharomyces cerevisiae is a proven host for the commercial production of recombinant biopharmaceutical proteins. For the manufacture of heterologous proteins with activities deleterious to the host it can be desirable to minimise production during the growth phase and ind...

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Detalles Bibliográficos
Autores principales: Møller, Thea S. B., Hay, Joanna, Saxton, Malcolm J., Bunting, Karen, Petersen, Evamaria I., Kjærulff, Søren, Finnis, Christopher J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241953/
https://www.ncbi.nlm.nih.gov/pubmed/28100236
http://dx.doi.org/10.1186/s12934-017-0627-7