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Genetic effect of interleukin-1 beta (C-511T) polymorphism on the structural covariance network and white matter integrity in Alzheimer’s disease

BACKGROUND: Inflammatory processes play a pivotal role in the degenerative process of Alzheimer’s disease. In humans, a biallelic (C/T) polymorphism in the promoter region (position-511) (rs16944) of the interleukin-1 beta gene has been significantly associated with differences in the secretory capa...

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Detalles Bibliográficos
Autores principales: Huang, Chi-Wei, Hsu, Shih-Wei, Tsai, Shih-Jen, Chen, Nai-Ching, Liu, Mu-En, Lee, Chen-Chang, Huang, Shu-Hua, Chang, Weng-Neng, Chang, Ya-Ting, Tsai, Wan-Chen, Chang, Chiung-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242022/
https://www.ncbi.nlm.nih.gov/pubmed/28100246
http://dx.doi.org/10.1186/s12974-017-0791-z