Identification and application of anti-inflammatory compounds screening system based on RAW264.7 cells stably expressing NF-κB-dependent SEAP reporter gene

BACKGROUND: NF-κB is one of the key transcription factors in the inflammatory response, transactivates a series of pro-inflammatory genes and is therefore regarded as an important target for anti-inflammatory drug screening. METHOD: We recombined the reporter gene vector with inserting the “neo” tra...

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Detalles Bibliográficos
Autores principales: Li, Yue, Wang, Xiaomeng, Ren, Juan, Lan, Xi, Li, Jing, Yi, Jing, Liu, Li, Han, Yan, Zhang, Sanqi, Li, Dongmin, Lu, Shemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242024/
https://www.ncbi.nlm.nih.gov/pubmed/28095903
http://dx.doi.org/10.1186/s40360-016-0113-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242024/
https://www.ncbi.nlm.nih.gov/pubmed/28095903
http://dx.doi.org/10.1186/s40360-016-0113-6

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