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Teleocidin A2 inhibits human proteinase‐activated receptor 2 signaling in tumor cells

Enhanced expression of the proteinase‐activated receptor 2 (PAR2) is linked to cell proliferation and migration in many cancer cell types. The role of PAR2 in cancer progression strongly illustrates the need for PAR2‐inhibiting compounds. However, to date, potent and selective PAR2 antagonists have...

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Detalles Bibliográficos
Autores principales: Stahn, Sonja, Thelen, Lisa, Albrecht, Ina‐Maria, Bitzer, Jens, Henkel, Thomas, Teusch, Nicole Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242168/
https://www.ncbi.nlm.nih.gov/pubmed/28116092
http://dx.doi.org/10.1002/prp2.230