Cargando…

Induction of K562 Cell Apoptosis by As(4)S(4) via Down-Regulating miR181

BACKGROUND: Chronic myelogenous leukemia (CML) has unsatisfactory treatment efficacy at present. As the major component of red orpiment, tetra-arsenic tetra-sulfide (As(4)S(4)) has been recently used in treating leukemia, but with unclear mechanism targeting CML. MicroRNA (miR) is a group of endogen...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Jiangjiang, Zheng, Shunli, Zhang, Lei, Wang, Yi, Meng, Jiali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242199/
https://www.ncbi.nlm.nih.gov/pubmed/28072759
http://dx.doi.org/10.12659/MSM.899214