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Induction of K562 Cell Apoptosis by As(4)S(4) via Down-Regulating miR181
BACKGROUND: Chronic myelogenous leukemia (CML) has unsatisfactory treatment efficacy at present. As the major component of red orpiment, tetra-arsenic tetra-sulfide (As(4)S(4)) has been recently used in treating leukemia, but with unclear mechanism targeting CML. MicroRNA (miR) is a group of endogen...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242199/ https://www.ncbi.nlm.nih.gov/pubmed/28072759 http://dx.doi.org/10.12659/MSM.899214 |