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Induction of K562 Cell Apoptosis by As(4)S(4) via Down-Regulating miR181

BACKGROUND: Chronic myelogenous leukemia (CML) has unsatisfactory treatment efficacy at present. As the major component of red orpiment, tetra-arsenic tetra-sulfide (As(4)S(4)) has been recently used in treating leukemia, but with unclear mechanism targeting CML. MicroRNA (miR) is a group of endogen...

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Detalles Bibliográficos
Autores principales:	Gong, Jiangjiang, Zheng, Shunli, Zhang, Lei, Wang, Yi, Meng, Jiali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242199/ https://www.ncbi.nlm.nih.gov/pubmed/28072759 http://dx.doi.org/10.12659/MSM.899214

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