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Robust, universal biomarker assay to detect senescent cells in biological specimens

Cellular senescence contributes to organismal development, aging, and diverse pathologies, yet available assays to detect senescent cells remain unsatisfactory. Here, we designed and synthesized a lipophilic, biotin‐linked Sudan Black B (SBB) analogue suitable for sensitive and specific, antibody‐en...

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Detalles Bibliográficos
Autores principales: Evangelou, Konstantinos, Lougiakis, Nikolaos, Rizou, Sophia V., Kotsinas, Athanassios, Kletsas, Dimitris, Muñoz‐Espín, Daniel, Kastrinakis, Nikolaos G, Pouli, Nicole, Marakos, Panagiotis, Townsend, Paul, Serrano, Manuel, Bartek, Jiri, Gorgoulis, Vassilis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242262/
https://www.ncbi.nlm.nih.gov/pubmed/28165661
http://dx.doi.org/10.1111/acel.12545