Senescence‐associated DNA methylation is stochastically acquired in subpopulations of mesenchymal stem cells

Replicative senescence has a major impact on function and integrity of cell preparations. This process is reflected by continuous DNA methylation (DNAm) changes at specific CpG dinucleotides in the course of in vitro culture, and such modifications can be used to estimate the state of cellular senes...

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Detalles Bibliográficos
Autores principales: Franzen, Julia, Zirkel, Anne, Blake, Jonathon, Rath, Björn, Benes, Vladimir, Papantonis, Argyris, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242294/
https://www.ncbi.nlm.nih.gov/pubmed/27785870
http://dx.doi.org/10.1111/acel.12544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242294/
https://www.ncbi.nlm.nih.gov/pubmed/27785870
http://dx.doi.org/10.1111/acel.12544

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