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Antioxidants reveal an inverted U‐shaped dose‐response relationship between reactive oxygen species levels and the rate of aging in Caenorhabditis elegans

Reactive oxygen species (ROS) are potentially toxic, but they are also signaling molecules that modulate aging. Recent observations that ROS can promote longevity have to be reconciled with the numerous claims about the benefits of antioxidants on lifespan. Here, three antioxidants [N‐acetylcysteine...

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Detalles Bibliográficos
Autores principales: Desjardins, David, Cacho‐Valadez, Briseida, Liu, Ju‐Ling, Wang, Ying, Yee, Callista, Bernard, Kristine, Khaki, Arman, Breton, Lionel, Hekimi, Siegfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242296/
https://www.ncbi.nlm.nih.gov/pubmed/27683245
http://dx.doi.org/10.1111/acel.12528