Uncoupling associations of risk alleles with endophenotypes and phenotypes: insights from the ApoB locus and heart‐related traits

Traditionally, genomewide association studies (GWAS) have emphasized the benefits of large samples in the analyses of age‐related traits rather than their specific properties. We adopted a realistic concept of genetic susceptibility to inherently heterogeneous, age‐related traits driven by the elusi...

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Detalles Bibliográficos
Autores principales: Kulminski, Alexander M., Kernogitski, Yelena, Culminskaya, Irina, Loika, Yury, Arbeev, Konstantin G., Bagley, Olivia, Duan, Matt, Arbeeva, Liubov, Ukraintseva, Svetlana V., Wu, Deqing, Stallard, Eric, Yashin, Anatoliy I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242299/
https://www.ncbi.nlm.nih.gov/pubmed/27683205
http://dx.doi.org/10.1111/acel.12526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242299/
https://www.ncbi.nlm.nih.gov/pubmed/27683205
http://dx.doi.org/10.1111/acel.12526

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