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Uncoupling associations of risk alleles with endophenotypes and phenotypes: insights from the ApoB locus and heart‐related traits
Traditionally, genomewide association studies (GWAS) have emphasized the benefits of large samples in the analyses of age‐related traits rather than their specific properties. We adopted a realistic concept of genetic susceptibility to inherently heterogeneous, age‐related traits driven by the elusi...
Autores principales: | Kulminski, Alexander M., Kernogitski, Yelena, Culminskaya, Irina, Loika, Yury, Arbeev, Konstantin G., Bagley, Olivia, Duan, Matt, Arbeeva, Liubov, Ukraintseva, Svetlana V., Wu, Deqing, Stallard, Eric, Yashin, Anatoliy I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242299/ https://www.ncbi.nlm.nih.gov/pubmed/27683205 http://dx.doi.org/10.1111/acel.12526 |
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