mTOR regulates the expression of DNA damage response enzymes in long‐lived Snell dwarf, GHRKO, and PAPPA‐KO mice

Studies of the mTOR pathway have prompted speculation that diminished mTOR complex‐1 (mTORC1) function may be involved in controlling the aging process. Our previous studies have shown diminished mTORC1 activity in tissues of three long‐lived mutant mice: Snell dwarf mice, growth hormone receptor ge...

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Detalles Bibliográficos
Autores principales: Dominick, Graham, Bowman, Jacqueline, Li, Xinna, Miller, Richard A., Garcia, Gonzalo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242303/
https://www.ncbi.nlm.nih.gov/pubmed/27618784
http://dx.doi.org/10.1111/acel.12525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242303/
https://www.ncbi.nlm.nih.gov/pubmed/27618784
http://dx.doi.org/10.1111/acel.12525

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