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mTOR regulates the expression of DNA damage response enzymes in long‐lived Snell dwarf, GHRKO, and PAPPA‐KO mice
Studies of the mTOR pathway have prompted speculation that diminished mTOR complex‐1 (mTORC1) function may be involved in controlling the aging process. Our previous studies have shown diminished mTORC1 activity in tissues of three long‐lived mutant mice: Snell dwarf mice, growth hormone receptor ge...
Autores principales: | Dominick, Graham, Bowman, Jacqueline, Li, Xinna, Miller, Richard A., Garcia, Gonzalo G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242303/ https://www.ncbi.nlm.nih.gov/pubmed/27618784 http://dx.doi.org/10.1111/acel.12525 |
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