DNA polymerase β decrement triggers death of olfactory bulb cells and impairs olfaction in a mouse model of Alzheimer's disease

Alzheimer's disease (AD) involves the progressive degeneration of neurons critical for learning and memory. In addition, patients with AD typically exhibit impaired olfaction associated with neuronal degeneration in the olfactory bulb (OB). Because DNA base excision repair (BER) is reduced in b...

Descripción completa

Detalles Bibliográficos
Autores principales: Misiak, Magdalena, Vergara Greeno, Rebeca, Baptiste, Beverly A., Sykora, Peter, Liu, Dong, Cordonnier, Stephanie, Fang, Evandro F., Croteau, Deborah L., Mattson, Mark P., Bohr, Vilhelm A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242308/
https://www.ncbi.nlm.nih.gov/pubmed/27686631
http://dx.doi.org/10.1111/acel.12541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242308/
https://www.ncbi.nlm.nih.gov/pubmed/27686631
http://dx.doi.org/10.1111/acel.12541

Ejemplares similares