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Opposing impacts on healthspan and longevity by limiting dietary selenium in telomere dysfunctional mice

Selenium (Se) is a trace metalloid essential for life, but its nutritional and physiological roles during the aging process remain elusive. While telomere attrition contributes to replicative senescence mainly through persistent DNA damage response, such an aging process is mitigated in mice with in...

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Detalles Bibliográficos
Autores principales: Wu, Ryan T., Cao, Lei, Mattson, Elliot, Witwer, Kenneth W., Cao, Jay, Zeng, Huawei, He, Xin, Combs, Gerald F., Cheng, Wen‐Hsing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242309/
https://www.ncbi.nlm.nih.gov/pubmed/27653523
http://dx.doi.org/10.1111/acel.12529