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Use of restrained molecular dynamics to predict the conformations of phosphorylated receiver domains in two‐component signaling systems

Two‐component signaling (TCS) is the primary means by which bacteria, as well as certain plants and fungi, respond to external stimuli. Signal transduction involves stimulus‐dependent autophosphorylation of a sensor histidine kinase and phosphoryl transfer to the receiver domain of a downstream resp...

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Detalles Bibliográficos
Autores principales: Foster, Clay A., West, Ann H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242315/
https://www.ncbi.nlm.nih.gov/pubmed/27802580
http://dx.doi.org/10.1002/prot.25207