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Exacerbated Leishmaniasis Caused by a Viral Endosymbiont can be Prevented by Immunization with Its Viral Capsid

Recent studies have shown that a cytoplasmic virus called Leishmaniavirus (LRV) is present in some Leishmania species and acts as a potent innate immunogen, aggravating lesional inflammation and development in mice. In humans, the presence of LRV in Leishmania guyanensis and in L. braziliensis was s...

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Detalles Bibliográficos
Autores principales: Castiglioni, Patrik, Hartley, Mary-Anne, Rossi, Matteo, Prevel, Florence, Desponds, Chantal, Utzschneider, Daniel T., Eren, Remzi-Onur, Zangger, Haroun, Brunner, Livia, Collin, Nicolas, Zehn, Dietmar, Kuhlmann, F. Matthew, Beverley, Stephen M., Fasel, Nicolas, Ronet, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242429/
https://www.ncbi.nlm.nih.gov/pubmed/28099431
http://dx.doi.org/10.1371/journal.pntd.0005240