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ALK gene expression status in pleural effusion predicts tumor responsiveness to crizotinib in Chinese patients with lung adenocarcinoma

OBJECTIVE: The relationship between anaplastic lymphoma kinase (ALK) expression in malignant pleural effusion (MPE) samples detected only by Ventana immunohistochemistry (IHC) ALK (D5F3) and the efficacy of ALK-tyrosine kinase inhibitor therapy is uncertain. METHODS: Ventana anti-ALK (D5F3) rabbit m...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Wu, Xiaonan, Han, Xiaohong, Cheng, Gang, Mu, Xinlin, Zhang, Yuhui, Cui, Di, Liu, Chang, Liu, Dongge, Shi, Yuankai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242450/
https://www.ncbi.nlm.nih.gov/pubmed/28174489
http://dx.doi.org/10.21147/j.issn.1000-9604.2016.06.07