Regulation of NUB1 Activity through Non-Proteolytic Mdm2-Mediated Ubiquitination

NUB1 (Nedd8 ultimate buster 1) is an adaptor protein which negatively regulates the ubiquitin-like protein Nedd8 as well as neddylated proteins levels through proteasomal degradation. However, molecular mechanisms underlying this function are not completely understood. Here, we report that the oncog...

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Detalles Bibliográficos
Autores principales: Bonacci, Thomas, Audebert, Stéphane, Camoin, Luc, Baudelet, Emilie, Iovanna, Juan-Lucio, Soubeyran, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242482/
https://www.ncbi.nlm.nih.gov/pubmed/28099510
http://dx.doi.org/10.1371/journal.pone.0169988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242482/
https://www.ncbi.nlm.nih.gov/pubmed/28099510
http://dx.doi.org/10.1371/journal.pone.0169988

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