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Regulation of NUB1 Activity through Non-Proteolytic Mdm2-Mediated Ubiquitination
NUB1 (Nedd8 ultimate buster 1) is an adaptor protein which negatively regulates the ubiquitin-like protein Nedd8 as well as neddylated proteins levels through proteasomal degradation. However, molecular mechanisms underlying this function are not completely understood. Here, we report that the oncog...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242482/ https://www.ncbi.nlm.nih.gov/pubmed/28099510 http://dx.doi.org/10.1371/journal.pone.0169988 |