A Signature of Genomic Instability Resulting from Deficient Replication Licensing

Insufficient licensing of DNA replication origins has been shown to result in genome instability, stem cell deficiency, and cancers. However, it is unclear whether the DNA damage resulting from deficient replication licensing occurs generally or if specific sites are preferentially affected. To map...

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Detalles Bibliográficos
Autores principales: Pruitt, Steven C., Qin, Maochun, Wang, Jianmin, Kunnev, Dimiter, Freeland, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242545/
https://www.ncbi.nlm.nih.gov/pubmed/28045896
http://dx.doi.org/10.1371/journal.pgen.1006547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242545/
https://www.ncbi.nlm.nih.gov/pubmed/28045896
http://dx.doi.org/10.1371/journal.pgen.1006547

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