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A Signature of Genomic Instability Resulting from Deficient Replication Licensing
Insufficient licensing of DNA replication origins has been shown to result in genome instability, stem cell deficiency, and cancers. However, it is unclear whether the DNA damage resulting from deficient replication licensing occurs generally or if specific sites are preferentially affected. To map...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242545/ https://www.ncbi.nlm.nih.gov/pubmed/28045896 http://dx.doi.org/10.1371/journal.pgen.1006547 |