Mitochondrial respiratory gene expression is suppressed in many cancers

The fundamental metabolic decision of a cell, the balance between respiration and fermentation, rests in part on expression of the mitochondrial genome (mtDNA) and coordination with expression of the nuclear genome (nuDNA). Previously we described mtDNA copy number depletion across many solid tumor...

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Detalles Bibliográficos
Autores principales: Reznik, Ed, Wang, Qingguo, La, Konnor, Schultz, Nikolaus, Sander, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243113/
https://www.ncbi.nlm.nih.gov/pubmed/28099114
http://dx.doi.org/10.7554/eLife.21592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243113/
https://www.ncbi.nlm.nih.gov/pubmed/28099114
http://dx.doi.org/10.7554/eLife.21592

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