PUMA and NF-kB Are Cell Signaling Predictors of Reovirus Oncolysis of Breast Cancer

BACKGROUND AND PURPOSE: Reovirus is a ubiquitous RNA virus that exploits aberrant signaling pathways for its replication. The oncolytic potential of reovirus against numerous cancers under pre-clinical/clinical conditions has been documented by us and others. Despite its proven clinical activity, th...

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Detalles Bibliográficos
Autores principales: Thirukkumaran, Chandini, Shi, Zhong-Qiao, Thirukkumaran, Ponnampalam, Luider, Joanne, Kopciuk, Karen, Spurrell, Jason, Elzinga, Kate, Morris, Don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243128/
https://www.ncbi.nlm.nih.gov/pubmed/28099441
http://dx.doi.org/10.1371/journal.pone.0168233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243128/
https://www.ncbi.nlm.nih.gov/pubmed/28099441
http://dx.doi.org/10.1371/journal.pone.0168233

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