Septin 7 reduces nonmuscle myosin IIA activity in the SNAP23 complex and hinders GLUT4 storage vesicle docking and fusion

Glomerular epithelial cells, podocytes, are insulin responsive and can develop insulin resistance. Here, we demonstrate that the small GTPase septin 7 forms a complex with nonmuscle myosin heavy chain IIA (NMHC-IIA; encoded by MYH9), a component of the nonmuscle myosin IIA (NM-IIA) hexameric complex...

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Detalles Bibliográficos
Autores principales: Wasik, Anita A., Dumont, Vincent, Tienari, Jukka, Nyman, Tuula A., Fogarty, Christopher L., Forsblom, Carol, Lehto, Markku, Lehtonen, Eero, Groop, Per-Henrik, Lehtonen, Sanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243148/
https://www.ncbi.nlm.nih.gov/pubmed/28011197
http://dx.doi.org/10.1016/j.yexcr.2016.12.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243148/
https://www.ncbi.nlm.nih.gov/pubmed/28011197
http://dx.doi.org/10.1016/j.yexcr.2016.12.010

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