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Septin 7 reduces nonmuscle myosin IIA activity in the SNAP23 complex and hinders GLUT4 storage vesicle docking and fusion
Glomerular epithelial cells, podocytes, are insulin responsive and can develop insulin resistance. Here, we demonstrate that the small GTPase septin 7 forms a complex with nonmuscle myosin heavy chain IIA (NMHC-IIA; encoded by MYH9), a component of the nonmuscle myosin IIA (NM-IIA) hexameric complex...
Autores principales: | Wasik, Anita A., Dumont, Vincent, Tienari, Jukka, Nyman, Tuula A., Fogarty, Christopher L., Forsblom, Carol, Lehto, Markku, Lehtonen, Eero, Groop, Per-Henrik, Lehtonen, Sanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243148/ https://www.ncbi.nlm.nih.gov/pubmed/28011197 http://dx.doi.org/10.1016/j.yexcr.2016.12.010 |
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