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Few amino acid positions in rpoB are associated with most of the rifampin resistance in Mycobacterium tuberculosis
BACKGROUND: Mutations in rpoB, the gene encoding the β subunit of DNA-dependent RNA polymerase, are associated with rifampin resistance in Mycobacterium tuberculosis. Several studies have been conducted where minimum inhibitory concentration (MIC, which is defined as the minimum concentration of the...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524371/ https://www.ncbi.nlm.nih.gov/pubmed/15453919 http://dx.doi.org/10.1186/1471-2105-5-137 |