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Few amino acid positions in rpoB are associated with most of the rifampin resistance in Mycobacterium tuberculosis

BACKGROUND: Mutations in rpoB, the gene encoding the β subunit of DNA-dependent RNA polymerase, are associated with rifampin resistance in Mycobacterium tuberculosis. Several studies have been conducted where minimum inhibitory concentration (MIC, which is defined as the minimum concentration of the...

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Detalles Bibliográficos
Autores principales: Cummings, Michael P, Segal, Mark R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524371/
https://www.ncbi.nlm.nih.gov/pubmed/15453919
http://dx.doi.org/10.1186/1471-2105-5-137