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The fallacy of enrolling only high-risk subjects in cancer prevention trials: Is there a "free lunch"?

BACKGROUND: There is a common belief that most cancer prevention trials should be restricted to high-risk subjects in order to increase statistical power. This strategy is appropriate if the ultimate target population is subjects at the same high-risk. However if the target population is the general...

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Detalles Bibliográficos
Autores principales: Baker, Stuart G, Kramer, Barnett S, Corle, Donald
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524373/
https://www.ncbi.nlm.nih.gov/pubmed/15461821
http://dx.doi.org/10.1186/1471-2288-4-24