Acute Depletion of D2 Receptors from the Rat Substantia Nigra Alters Dopamine Kinetics in the Dorsal Striatum and Drug Responsivity

Recent studies have used conditional knockout mice to selectively delete the D2 autoreceptor; however, these approaches result in global deletion of D2 autoreceptors early in development. The present study takes a different approach using RNA interference (RNAi) to knockdown the expression of the D2...

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Detalles Bibliográficos
Autores principales: Budygin, Evgeny A., Oleson, Erik B., Lee, Yun Beom, Blume, Lawrence C., Bruno, Michael J., Howlett, Allyn C., Thompson, Alexis C., Bass, Caroline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243821/
https://www.ncbi.nlm.nih.gov/pubmed/28154530
http://dx.doi.org/10.3389/fnbeh.2016.00248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243821/
https://www.ncbi.nlm.nih.gov/pubmed/28154530
http://dx.doi.org/10.3389/fnbeh.2016.00248

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