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Acute Depletion of D2 Receptors from the Rat Substantia Nigra Alters Dopamine Kinetics in the Dorsal Striatum and Drug Responsivity
Recent studies have used conditional knockout mice to selectively delete the D2 autoreceptor; however, these approaches result in global deletion of D2 autoreceptors early in development. The present study takes a different approach using RNA interference (RNAi) to knockdown the expression of the D2...
Autores principales: | Budygin, Evgeny A., Oleson, Erik B., Lee, Yun Beom, Blume, Lawrence C., Bruno, Michael J., Howlett, Allyn C., Thompson, Alexis C., Bass, Caroline E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243821/ https://www.ncbi.nlm.nih.gov/pubmed/28154530 http://dx.doi.org/10.3389/fnbeh.2016.00248 |
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