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β-Caryophyllene/Hydroxypropyl-β-Cyclodextrin Inclusion Complex Improves Cognitive Deficits in Rats with Vascular Dementia through the Cannabinoid Receptor Type 2 -Mediated Pathway

This work was conducted to prepare β-caryophyllene-hydroxypropyl-β-cyclodextrin inclusion complex (HPβCD/BCP) and investigate its effects and mechanisms on cognitive deficits in vascular dementia (VD) rats. First, HPβCD/BCP was prepared, optimized, characterized, and evaluated. HPβCD/BCP and AM630 w...

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Detalles Bibliográficos
Autores principales: Lou, Jie, Teng, Zhipeng, Zhang, Liangke, Yang, Jiadan, Ma, Lianju, Wang, Fang, Tian, Xiaocui, An, Ruidi, Yang, Mei, Zhang, Qian, Xu, Lu, Dong, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243824/
https://www.ncbi.nlm.nih.gov/pubmed/28154534
http://dx.doi.org/10.3389/fphar.2017.00002