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Deletion of Type 3 Adenylyl Cyclase Perturbs the Postnatal Maturation of Olfactory Sensory Neurons and Olfactory Cilium Ultrastructure in Mice

Type 3 adenylyl cyclase (Adcy3) is localized to the cilia of olfactory sensory neurons (OSNs) and is an essential component of the olfactory cyclic adenosine monophosphate (cAMP) signaling pathway. Although the role of this enzyme in odor detection and axonal projection in OSNs was previously charac...

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Detalles Bibliográficos
Autores principales: Zhang, Zhe, Yang, Dong, Zhang, Mengdi, Zhu, Ning, Zhou, Yanfen, Storm, Daniel R., Wang, Zhenshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243839/
https://www.ncbi.nlm.nih.gov/pubmed/28154525
http://dx.doi.org/10.3389/fncel.2017.00001