Cargando…

Deletion of Type 3 Adenylyl Cyclase Perturbs the Postnatal Maturation of Olfactory Sensory Neurons and Olfactory Cilium Ultrastructure in Mice

Type 3 adenylyl cyclase (Adcy3) is localized to the cilia of olfactory sensory neurons (OSNs) and is an essential component of the olfactory cyclic adenosine monophosphate (cAMP) signaling pathway. Although the role of this enzyme in odor detection and axonal projection in OSNs was previously charac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Zhe, Yang, Dong, Zhang, Mengdi, Zhu, Ning, Zhou, Yanfen, Storm, Daniel R., Wang, Zhenshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243839/ https://www.ncbi.nlm.nih.gov/pubmed/28154525 http://dx.doi.org/10.3389/fncel.2017.00001

Ejemplares similares

Gene Expression Profiles of Main Olfactory Epithelium in Adenylyl Cyclase 3 Knockout Mice
por: Wang, Zhenshan, et al.
Publicado: (2015)

The Type 3 Adenylyl Cyclase Is Required for the Survival and Maturation of Newly Generated Granule Cells in the Olfactory Bulb
por: Luo, Jie, et al.
Publicado: (2015)

Maternal Behavior is Impaired in Female Mice Lacking Type 3 Adenylyl Cyclase
por: Wang, Zhenshan, et al.
Publicado: (2011)

Mechanisms of Regulation of Olfactory Transduction and Adaptation in the Olfactory Cilium
por: Antunes, Gabriela, et al.
Publicado: (2014)

Adult Type 3 Adenylyl Cyclase–Deficient Mice Are Obese
por: Wang, Zhenshan, et al.
Publicado: (2009)

Sequential Maturation of Olfactory Sensory Neurons in the Mature Olfactory Epithelium
por: Liberia, Teresa, et al.
Publicado: (2019)

The role of ciliopathy-associated type 3 adenylyl cyclase in infanticidal behavior in virgin adult male mice
por: Wu, Xiangbo, et al.
Publicado: (2022)

Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High‐Fat Diet‐Induced Obesity Mediated by Autophagy
por: Yang, Dong, et al.
Publicado: (2021)

Disruption of type 3 adenylyl cyclase expression in the hypothalamus leads to obesity
por: Cao, Hong, et al.
Publicado: (2016)

Role of adenylyl cyclase in reduced β-adrenoceptor-mediated vasorelaxation during maturation
por: López-Canales, O.A., et al.
Publicado: (2016)

New Perspectives on Plant Adenylyl Cyclases
por: Ruzvidzo, Oziniel, et al.
Publicado: (2019)

Expression and functions of adenylyl cyclases in the CNS
por: Devasani, Karan, et al.
Publicado: (2022)

Expansion of murine and human olfactory epithelium/mucosa colonies and generation of mature olfactory sensory neurons under chemically defined conditions
por: Ren, Wenwen, et al.
Publicado: (2021)

Function of Adenylyl Cyclase in Heart: the AKAP Connection
por: Baldwin, Tanya A., et al.
Publicado: (2018)

Structural basis of adenylyl cyclase 9 activation
por: Qi, Chao, et al.
Publicado: (2022)

Protein kinase C sensitizes olfactory adenylate cyclase
Publicado: (1993)

A Group of Olfactory Receptor Alleles that Encode Full Length Proteins are Down-Regulated as Olfactory Sensory Neurons Mature
por: Krolewski, Richard C., et al.
Publicado: (2020)

Immature olfactory sensory neurons provide behaviourally relevant sensory input to the olfactory bulb
por: Huang, Jane S., et al.
Publicado: (2022)

Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6
por: Bull Melsom, Caroline, et al.
Publicado: (2019)

The role of a ciliary GTPase in the regulation of neuronal maturation of olfactory sensory neurons
por: Habif, Julien C., et al.
Publicado: (2023)

Pcdh19 mediates olfactory sensory neuron coalescence during postnatal stages and regeneration
por: Martinez, Andrew P., et al.
Publicado: (2023)

Transduction and Adaptation Mechanisms in the Cilium or Microvilli of Photoreceptors and Olfactory Receptors From Insects to Humans
por: Abbas, Fatima, et al.
Publicado: (2021)

Kinesin-2 transports Orco into the olfactory cilium of Drosophila melanogaster at specific developmental stages
por: Jana, Swadhin Chandra, et al.
Publicado: (2021)

Olfactory sensory axons target specific protoglomeruli in the olfactory bulb of zebrafish
por: Shao, Xin, et al.
Publicado: (2017)

Lhx2 Determines Odorant Receptor Expression Frequency in Mature Olfactory Sensory Neurons
por: Zhang, Guangfan, et al.
Publicado: (2016)

Insulin-Dependent Maturation of Newly Generated Olfactory Sensory Neurons after Injury
por: Kuboki, Akihito, et al.
Publicado: (2021)

Activation of adenylyl cyclase in Chlamydomonas reinhardtii by adhesion and by heat
Publicado: (1993)

Soluble adenylyl cyclase is essential for proper lysosomal acidification
por: Rahman, Nawreen, et al.
Publicado: (2016)

Editorial: Adenylyl cyclase isoforms as potential drug targets
por: Brust, Tarsis F., et al.
Publicado: (2022)

Postnatal Development of Centrifugal Inputs to the Olfactory Bulb
por: Kostka, Johanna K., et al.
Publicado: (2022)

Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression
por: Ledderose, Julia, et al.
Publicado: (2013)

Olfactory sensory neurons transiently express multiple olfactory receptors during development
por: Tan, Longzhi, et al.
Publicado: (2015)

Odor-evoked inhibition of olfactory sensory neurons drives olfactory perception in Drosophila
por: Cao, Li-Hui, et al.
Publicado: (2017)

Inducible and Targeted Deletion of the ERK5 MAP Kinase in Adult Neurogenic Regions Impairs Adult Neurogenesis in the Olfactory Bulb and Several Forms of Olfactory Behavior
por: Pan, Yung-Wei, et al.
Publicado: (2012)

Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting
por: Rich, Constance A., et al.
Publicado: (2018)

Chemostimuli for guanylyl cyclase-D-expressing olfactory sensory neurons promote the acquisition of preferences for foods adulterated with the rodenticide warfarin
por: Kelliher, Kevin R., et al.
Publicado: (2015)

Lack of an effect of nephron-specific deletion of adenylyl cyclase 3 on renal sodium and water excretion or arterial pressure
por: Kittikulsuth, Wararat, et al.
Publicado: (2015)

Mechanism of olfactory masking in the sensory cilia
por: Takeuchi, Hiroko, et al.
Publicado: (2009)

Correction: Inducible and Targeted Deletion of the ERK5 MAP Kinase in Adult Neurogenic Regions Impairs Adult Neurogenesis in the Olfactory Bulb and Several Forms of Olfactory Behavior
por: Pan, Yung-Wei, et al.
Publicado: (2013)

Selective ablation of type 3 adenylyl cyclase in somatostatin-positive interneurons produces anxiety- and depression-like behaviors in mice
por: Yang, Xiao-Yu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_nanialjpfmp6gak64f82qd4vsn